WebCyclophosphamide is an alkylating drug indicated for treatment of: ... 12.1 Mechanism of Action . 12.2 Pharmacodynamics . 12.3 Pharmacokinetics . 13 NONCLINICAL TOXICOLOGY . 13.1. Carcinogenesis, Mutagenesis, Impairment of Fertility . 15 REFERENCES 16 HOW SUPPLIED/STORAGE AND HANDLING WebOct 6, 2016 · Cytotoxic agents can cause nephrotoxicity by a variety of mechanisms. While many drugs induce a fall in the glomerular filtration rate (GFR) that is dose-related and predictable, others are associated with a more protracted decline in renal function, which is often irreversible. Platinum derivatives
Cyclophosphamide (Cytoxan) : Johns Hopkins Vasculitis Center
WebSep 22, 2016 · Cyclophosphamide 0.3-1.0 g/m 2 IV repeated once every 2 to 4 weeks × 1 to 3 doses; 50-200 mg orally once per day; after response has been achieved, dose can be tapered to 50 mg 24-85 1-16 wk Neutropenia, nausea/vomiting, infertility, secondary malignancy Danazol 50-800 mg/d orally divided into 2 to 4 doses per day 10-70 3-6 mo WebAug 19, 2024 · Cytoxan (cyclophosphamide) and its metabolites are dialyzable. Therefore, rapid hemodialysis is indicated when treating any suicidal or accidental … christina whitlock baseball
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WebOther Trade Name: Neosar ®. Cyclophosphamide is the generic name for the trade name drug Cytoxan or Neosar. In some cases, health care professionals may use the trade name Cytoxan or Neosar when referring to the generic drug name cyclophosphamide. Drug Type: Cyclophosphamide is an anti-cancer ("antineoplastic" or "cytotoxic") … WebCyclophosphamide is a cytotoxic (cytostatic), cell cycle nonspecific, antiproliferative agent which is used in such diverse medical problems as neoplasia, tissue transplantation and … WebNov 5, 2024 · Cyclophosphamide is an alkylating agent used in the treatment of several forms of cancer including leukemias, lymphomas and breast cancer. Cyclophosphamide therapy is associated with minor … gerber ultra flush toilets