Thymidine labeling index
WebbSummary The 3H-thymidine labelling index (3H-dT LI) ofcell suspensions from fresh material and the flow cytometric S-phase (FCM-S)ofnuclei recovered from paraffin … WebbThe data suggested, but did not prove, that a high LI was associated with more frequent metastasis to axillary lymph nodes, and it was suggested that the larger tumors were faster‐growing at the time of observation than the smaller tumors. A simple method for incubation of tissue specimens with tritiated thymidine under 3 atm oxygen tension gave …
Thymidine labeling index
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WebbIn contrast, when mice were given 17 repeated injections of 3H-thymidine at 6 hr intervals and killed 48 hr after the last injection, labeling indices in sialoadenectomized mice were significantly lower than those in sham-operated mice (35.3 +/- 4.3% vs 52.8 +/- 1.1% in the fundic gland area; 41.0 +/- 6.2% vs 55.1 +/- 5.9% in the pyloric gland ... WebbLabeling index measurements. The labeling index of cells in Matrigel threads after 6 d growth and the grain density of labeled cells were measured using a 3H-thymidine pulse labeling and autoradiography (Freyer and Suth-erland, 1980). Threads were labeled with 20 uCi/ml [H-3] thymidine (specific 1000 (A) Thread Diameter Thread Diameter 9L (B ...
WebbOf all the older techniques, however, the most important, by far, is the thymidine labeling index (TLI). 5 Here viable cells are exposed briefly in vitro to a radiolabeled precursor of DNA. The most common thymidine … Webb14 jan. 2024 · Scientific Reports - In vivo tracking of 14C thymidine labeled mesenchymal stem cells using ultra-sensitive accelerator mass spectrometry Skip to main content …
WebbThe thymidine labeling index (TLI) showed significantly higher median values in the cancer patients (3.48 per cent) than in the patients with benign diseases (1.02 per cent). TLI … Webb26 maj 2024 · Rapidly proliferating tumors were defined by thymidine labeling index (TLI) > 3% or histological grade 3 or S-phase > 10% or Ki67 > 20%. We analyze the subgroup of 466 patients with hormone receptor (HR)-positive tumors treated with sequential epirubicin/CMF regimens followed by tamoxifen and for whom immunohistochemical …
WebbThymidine labeling index (TLI), which is a kinetic parameter showing tumor aggressivity and cell proliferation rate, is shown among the secondary group of prognostic factors for breast cancer, and appears to be independent of the known prognostic Factors. Abstract: In addition to primary prognostic factors (tumor size, axillary lymph node status, …
WebbThe percentages of cells labelled with [^Hjthymidine (labelling index) and in mitosis (mitotic index) after each of the three pulses and the percentages of cells in metaphase after i and 3 h in colchicine after one and two pulses of non-radioactive thymidine at the labelling concentration are given in Table i. Table 2 sets out the durations of the the longest pandemicWebbIN VITRO DETERMINATION OF TRITIATED THYMIDINE LABEIJNG INDEX (LI) Evaluation of a Method Utilizing Hyperbaric Oxygen and Observations on the LI of Human Mammary Carcinoma JOHN S. MEYER, MD,* AND WALTER C. BAUER, MD~ A simple method for incubation of tissue specimens with tritiated thymidine under 3 atm oxygen tension gave … the longest of the mass textWebbAbstract Objective: The aim of this study is to determine the thymidine labeling index and its prognostic role in patients with ovarian cancer. Methods: Tumor cell proliferation in … the longest page in the worldWebbThymidine labeling index, flow cytometric S-phase measurement, and DNA index in human tumors. Comparisons and correlations The results of flow cytometry were compared … the longest pandemic in historyWebb3H-thymidine labeling index (TLI) was one of the first markers of proliferation used in breast cancer. The number of cells undergoing DNA synthesis is measured by 3 H-thymidine uptake using autoradiography for visualization. TLI represents the ratio between the number of labeled and all counted cells. tickhill furniture repairsWebb19 aug. 2007 · The aim of the present study was to determine the prognostic relevance of thymidine labeling index (TLI) in patients with breast cancer. TLI of the primary tumor was measured in 268 patients at... tickhill hairdressersWebbWe studied cellular proliferation by measuring the tritiated thymidine labeling index (TLI) in slices of primary invasive breast carcinomas. Estrogen receptor (ER) and progesterone … the longest palindrome word